Wide Local Excision Before Sentinel Lymph Node Biopsy in Melanoma

Author:

Tassavor Michael1,Bland Madalyn1,Goldenberg Olivia2,Tassavor Bryan3,Coldiron Brett1

Affiliation:

1. The Skin Cancer Center, Cincinnati, Ohio;

2. Tulane School of Medicine, New Orleans, Louisiana;

3. AT Still School of Osteopathic Medicine, Mesa, Arizona

Abstract

BACKGROUND Current guidelines suggest that wide local excision of thick melanomas be delayed until sentinel lymph node biopsies can be performed. OBJECTIVE To examine the literature and determine if there is a scientific basis for delaying wide local excision of thick melanomas. MATERIALS AND METHODS A narrative review of the literature was undertaken to examine all available studies on the subject. RESULTS There is no evidence that prior excision compromises sentinel lymph node identification. There are multiple unsubstantiated suggestions that large rotation flaps may lead to false negatives. CONCLUSION There is no basis for delaying wide local excision of thick melanomas until a sentinel lymph node biopsy can be performed.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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