Influencing factors, surgical management, and predictors of posterior fossa tumors with hydrocephalus in children

Author:

Feng Jiaqi12,Zhang Tianyi3,He Dake4,Mao Weiwei1,Wang Weiping5,Zhou Yabing6,Wang Xiaoqiang1

Affiliation:

1. Department of Pediatric Neurosurgery, School of Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China

2. Neurosurgery Deparrment, Graduate School, Inner Mongolia Medical University, Hohhot, China

3. Second School of Clinical Medicine, Shandong University, Jinan, China

4. Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

5. Department of Pediatric Critical Care Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

6. Department of Traditional Chinese medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

Abstract

Background: Hydrocephalus is a common disease in neurosurgery. In pediatric central nervous system tumors, the proportion of posterior fossa tumors (PFTs) in children is high, hydrocephalus is often the first manifestation, and some cases have de novo or aggravated hydrocephalus after surgery. Objective: To conclude some controversies about the treatment methods and timeline of PFT with hydrocephalus. Methods: This article reviews the latest progress in the literature and practical problems encountered in clinical practices. Results: For most children, surgical drainage is the most effective treatment; however, medical treatment can be performed before surgery or a definite diagnosis is made. In children with PFT, the risk of hydrocephalus can be initially predicted according to the condition of the child, which has clear clinical significance for the selection of treatment methods and the evaluation of related prognosis. Conclusion: PFT is a common site for CNS tumors in children, and its clinical manifestations are often hydrocephalus-related. According to the condition of pediatric patients, early prediction of the risk of hydrocephalus has clear clinical significance for the selection of treatment methods and the evaluation of related prognoses.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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