Pediatric onset myasthenia gravis with thymoma

Author:

Al Mohtasib Mohammad E.12,Abu Asbeh Yousef2,Abu Ihlayel Tuqa1,Hafiz Shayma1,Abu Alrub Yasmin1,Shammas Isam3,Bannoura Sami3,Abugharbieh Yazan3

Affiliation:

1. Palestine Polytechnic University

2. Thoracic Surgery Department

3. Al Ahli Hospital, Hebron, Palestine State of

Abstract

Introduction: The unusual combination of pediatric-onset myasthenia gravis (MG) with thymoma is exceedingly rare, with only around 11 reported cases from 1985 to 2020. Case Presentation: The authors present the case of a 6-year-old male patient diagnosed with MG and thymoma (histopathology: WHO type B2) who underwent complete surgical resection. Conclusion: Given its rarity and potential complications, it is essential to report this case to enhance the evidence base for pediatric MG patients. Imaging should be considered to rule out thymoma in such cases, and awareness of this uncommon condition should be raised among pediatricians, clinicians, and surgeons.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference18 articles.

1. Thymoma in childhood. A case report and review of literature;Nolasco-de la Rosa;Cirugía y Cirujanos (English Edition),2016

2. Mediastinal masses in children: experience with 120 cases;Gun;Pediatr Hematol Oncol,2012

3. Pediatric thymoma: a review and update of the literature;Rossi;Diagnostics,2022

4. The clinical features, diagnosis and management of recurrent thymoma;Luo;J Cardiothorac Surg,2016

5. Thymoma associated with autoimmune diseases: 85 cases and literature review;Bernard;Autoimmun Rev,2016

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