PharmGKB summary

Author:

Thorn Caroline F.,Aklillu Eleni,Klein Teri E.,Altman Russ B.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference50 articles.

1. Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.;Zhou;AAPS J,2009

2. A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.;Ueda;Mol Pharmacol,2006

3. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.;Shimada;J Pharmacol Exp Ther,1994

4. Functional pharmacogeneticsgenomics of human cytochromes P450 involved in drug biotransformation.;Zanger;Anal Bioanal Chem,2008

5. The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors.;Rasmussen;Pharmacogenetics,2002

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