New approaches in childhood asthma treatment

Author:

Castagnoli Riccardo12,Brambilla Ilaria12,Giovannini Mattia34,Marseglia Gian Luigi12,Licari Amelia12

Affiliation:

1. Pediatric Unit, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia

2. Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia

3. Allergy Unit, Meyer Children's Hospital IRCCS

4. Department of Health Sciences, University of Florence, Florence, Italy

Abstract

Purpose of review This review aims to summarize the most recent advances in asthma management, focusing on novel approaches to pediatric asthma. Recent findings In recent years, the therapeutic tools for pediatric asthma have expanded significantly for both the nonsevere and severe forms. The use of anti-inflammatory treatment, even for the mildest cases, and the withdrawal of symptomatic bronchodilation as monotherapy have been included in the most recent guidelines. Also, different biological therapies have revolutionized the therapeutical approach for severe uncontrolled asthma in children and adolescents. Summary With the expanding landscape of novel therapeutic approaches for pediatric asthma, further evidence is needed to help clinicians choose the best option for patients, particularly those with severe asthma. The identification of novel predictive biomarkers may also help pediatricians in selecting children and adolescents for innovative therapies.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Immunology,Immunology and Allergy

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