Effectiveness of Zhuang medicine medicated thread moxibustion on human xanthelasma – a case series

Author:

Jiang Yuan1,Suriyonplengsaeng Chinnawut2,Wu Mengyi3,Lin Jinran4,Liu Qingmei4,Zhou Yinghui4,Lin Jui-Ming4,Meesin Saowaluck5,Suwanchinda Atchima6,Wu Wenyu4,Thianthanyakij Traidit4ORCID

Affiliation:

1. Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China

2. Department of Anatomy, Faculty of Science, Mahidol University, Bangkok, Thailand

3. Shanghai University of Traditional Chinese Medicine, Shanghai, China

4. Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China

5. Faculty of Chinese Medicine, Huachiew Chalermprakiet University, Samutprakan, Thailand

6. Department of Dermatology, School of AntiAging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand.

Abstract

Rationale: Xanthelasma, characterized by yellowish plaques around the eyelids due to lipid deposits, is typically treated through invasive methods like laser therapy or surgery, which often leads to scarring and dyspigmentation. This case series investigates the potential of Zhuang medicine medicated thread moxibustion as a less invasive alternative. Patient Concerns: Three female patients, aged 34, 45, and 55, presented with non-tender, soft yellow plaques near the medial canthi of both upper eyelids. The lesions varied in size and had been present for durations ranging from 6 months to 2 years. These patients expressed concerns about the pain and potential adverse reactions associated with conventional treatments, opting instead for an alternative approach. Diagnoses: Each patient was diagnosed with xanthelasma based on clinical evaluation. Standard diagnostic tests returned normal results, confirming the absence of underlying systemic issues. Interventions: The treatment regimen involved Zhuang medicine medicated thread moxibustion applied at 10-day intervals for a total of three sessions. This traditional method was selected due to its minimally invasive nature. Outcomes: After the first session, patients experienced mild edema, which resolved within 24 h. A significant reduction in the size of the plaques was observed after the second session, and by the third session, there was complete resolution of the plaques. Throughout the treatment and follow-up period of 3 months, no adverse reactions or recurrence of the xanthelasma was noted. Lessons: This case series suggests that Zhuang medicine medicated thread moxibustion could be a safe and effective alternative for the treatment of xanthelasma, avoiding the complications associated with more invasive conventional methods. Further research involving larger sample sizes is recommended to validate these preliminary findings and possibly integrate this method into broader clinical practice.

Funder

National Science Foundation of China

National Key Research and Development Program of China

Leading Talent Project of Shanghai Health Comission

Jing'an District Clinical Advantage Special Disease Construction Project

Clinical Research Plan of SHDC

Shanghai Engineering Research Center of Hair Medicine

Shanghai Municipal Commission of Health and Family Planning

Shanghai Municipal Key Clinical Specialty

Publisher

Ovid Technologies (Wolters Kluwer Health)

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