Concurrent Benign Iodine-Avid Thymic and Liver Cysts Mimicking Metastatic Disease on 131I Whole-Body Scintigraphy-Reference-Cited by-同舟云学术

Concurrent Benign Iodine-Avid Thymic and Liver Cysts Mimicking Metastatic Disease on 131I Whole-Body Scintigraphy

Published:2024-01-15 Issue:3 Volume:49 Page:250-252
ISSN:1536-0229
Container-title:Clinical Nuclear Medicine
language:en
Short-container-title:Clin Nucl Med

Author:

Kamarulzaman Kamalia¹,Mohd Rohani Mohd Fazrin¹,Mat Nawi Norazlina²,Amir Hassan Siti Zarina¹

Affiliation:

1. Department of Nuclear Medicine, Hospital Kuala Lumpur, Lumpur

2. Department of Nuclear Medicine, Oncology, and Radiotherapy, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.

Abstract

Abstract A 57-year-old woman received radioiodine therapy post total thyroidectomy for pT3aNxMx follicular thyroid carcinoma. Posttherapy 131I whole-body scan showed 131I concentration in the chest, mediastinum, and left upper thigh with stimulated thyroglobulin (Tg) of 89 μg/L. Subsequent radioiodine therapies showed persistent 131I accumulation in the anterior mediastinal soft tissue lesions and a hypodense segment VII liver lesion visualized on SPECT/CT, suggestive of iodine-avid metastatic disease despite the undetectable serum Tg (<1.0 μg/L) with no Tg antibody interference. Biopsy of the liver lesion revealed liver cyst, and consequent removal of the mediastinal lesions showed benign thymic cysts.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference15 articles.

1. Orbital radioiodine uptake in epithelial conjunctival inclusion cyst on scintigraphy in a patient with differentiated thyroid cancer;Clin Nucl Med,2023

2. Epidermal cyst mimicking thyroid cancer metastasis;Clin Nucl Med,2023

3. A false positive I-131 metastatic survey caused by radioactive iodine uptake by a benign thymic cyst;Case Rep Endocrinol,2017

4. Pictorial review of false-positive results on radioiodine scintigrams of patients with differentiated thyroid cancer;Radiographics,2017

5. False-positive uptake on radioiodine whole-body scintigraphy: physiologic and pathologic variants unrelated to thyroid cancer;Am J Nucl Med Mol Imaging,2012

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Elevated 131I Activity in Adrenal Cyst in a Patient With Thyroid Cancer;Clinical Nuclear Medicine;2024-10

2. Localized 131I Uptake in the Deltoid Muscle Bilaterally After Parathyroid Transplantation;Clinical Nuclear Medicine;2024-08-15