Author:
Jung Miyeon,Smith Asa B.,Giordani Bruno,Clark David G.,Gradus-Pizlo Irmina,Wierenga Kelly L.,Lake Kittie Reid,Pressler Susan J.
Abstract
BackgroundCognitive dysfunction predicts mortality in heart failure (HF). Computerized cognitive training (CCT) has shown preliminary efficacy in improving cognitive function. However, the relationship between CCT and mortality is unclear. Aims were to evaluate (1) long-term efficacy of CCT in reducing 24-month mortality and (2) age, HF severity, global cognition, memory, working memory, depressive symptoms, and health-related quality of life as predictors of 24-month mortality among patients with HF.MethodsIn this prospective longitudinal study, 142 patients enrolled in a 3-arm randomized controlled trial were followed for 24 months. Logistic regression was used to achieve the aims.ResultsAcross 24 months, 16 patients died (CCT, 8.3%; control groups, 12.8%). Computerized cognitive training did not predict 24-month mortality (odds ratio [OR], 0.65). Older age (OR, 1.08), worse global cognition (OR, 0.73), memory (OR, 0.81), and depressive symptoms (OR, 1.10) at baseline predicted 24-month mortality.ConclusionsEfficacious interventions are needed to improve global cognition, memory, and depressive symptoms and reduce mortality in HF.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine
Reference62 articles.
1. Heart disease and stroke statistics—2022 update: a report from the American Heart Association;Circulation,2022
2. Global epidemiology and future trends of heart failure;AME Med J,2020
3. Brain axonal and myelin evaluation in heart failure;J Neurol Sci,2011
4. Reduced regional brain cortical thickness in patients with heart failure;PLoS One,2015
5. Regional hippocampal damage in heart failure;Eur J Heart Fail,2015
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献