Overview of pregnancy in solid-organ transplantation

Author:

Yenebere Priya1,Doraiswamy Mohankumar2,Gundroo Aijaz3

Affiliation:

1. Transplant Nephrology, Department of Internal Medicine, Indiana University, Indianapolis, Indiana

2. Nephrology - Critical Care, Department of Internal Medicine, Mercy Hospital, Fort Smith, Arkansas

3. Transplant Nephrology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

Abstract

Purpose of review Pregnancy in solid organ transplantation (SOT) is a very complex part of transplant medicine wherein there is scarce information available in the literature. Solid organ transplant recipients often have comorbidities, such as hypertension and diabetes, which add additional risk to a pregnancy. Recent findings We present this review article on the various aspects of different types of immunosuppressant medications used in pregnancy with added inputs on contraception and fertility after transplant. We described the antepartum and postpartum considerations and discussed the adverse effects of the immunosuppressive medications. Maternal and fetal complications of each SOT have been also discussed in this article. Summary This article will serve as the primary review articles for the use of immunosuppressive medications during pregnancy with consideration during pregnancy after SOT.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Transplantation,Immunology and Allergy

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