Extensive Cutaneous-Mucosal and Muscular Involvement of Gamma/Delta Cutaneous T-Cell Lymphoma on 18F-FDG PET/CT

Author:

Peslier Hugo1,Reichart Julien2,Boursot Charles2,Cohen-Tannugi Kevin2,Lacoeuille Franck1

Affiliation:

1. Nuclear Medicine, Centre Hospitalier Universitaire Angers, Angers, France

2. Centre Hospitalier du Mans, Le Mans, France.

Abstract

Abstract Gamma/delta T-cell lymphoma is a rare and aggressive subtype of primary cutaneous lymphoma. Clinical manifestations typically include the development of subcutaneous nodules and ulcerated plaques. Some forms present as panniculitis with hemophagocytic syndrome. Prognosis is bleak, with a 10% 5-year survival rate. In this report, we present the case of a 20-year-old man from French Polynesia, referred for 18F-FDG PET/CT because of the progressive worsening of febrile cutaneous-mucosal infiltration on the face persisting for 1 month. PET examination guided a biopsy from the right deltoid muscle, and expert histological analysis confirmed a CD8+ not otherwise specified T-cell lymphoma, granzyme+ and TCR gamma/delta.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference8 articles.

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2. Primary cutaneous gamma-delta T-cell lymphoma: a case report and review of literature;Cureus,2023

3. Clinical, diagnostic and prognostic characteristics of primary cutaneous gamma delta T-cell lymphomas;Clin Hematol Int,2022

4. Primary cutaneous gamma-delta T cell lymphomas: a case series and overview of the literature;Dermatopathology (Basel),2021

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