False-Positive Metastatic Bone Disease on FDG PET/CT Due to Multilevel Tophaceous Gout of the Spine

Author:

Drazyk Anna1,Loh Han,Bui Chuong1,Ding Pei,Mansberg Robert

Affiliation:

1. Department of Nuclear Medicine and PET, Nepean Hospital, Kingswood

Abstract

Abstract A 74-year-old woman was referred for 18F-FDG PET/CT for the evaluation of incidental CT finding of expansile destruction of left L4/5 facet joint with associated soft tissue mass concerning for a metastatic deposit. The FDG PET/CT revealed variable abnormally increased FDG activity involving multiple facet joints in all regions of the spine with corresponding expansile “punched-out” lytic lesions with sclerotic rims and overhanging margins on CT, raising the possibility of inflammatory polyarthropathy, including gout, as a differential diagnosis. Dual-energy CT of lumbar spine and CT-guided biopsy and culture of the left L4/5 facet joint demonstrated the presence of urate crystal deposition with no evidence of malignancy or infection, confirming the diagnosis of multilevel tophaceous gout of the spine.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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