Are We Approaching a Change in Paradigm in PET/CT Imaging of Solid Gastrointestinal (or Digestive) Tract Tumors With the Clinical Application of FAPI Imaging?

Author:

Delgado Bolton Roberto C.1ORCID,Calapaquí Terán Adriana K.2ORCID,Herrmann Ken3ORCID,Fanti Stefano4ORCID,Giammarile Francesco5ORCID

Affiliation:

1. Department of Diagnostic Imaging (Radiology) and Nuclear Medicine, University Hospital San Pedro and Centre for Biomedical Research of La Rioja (CIBIR), Logroño, La Rioja

2. Department of Pathology, University Hospital “Marqués de Valdecilla,” Santander, Spain

3. Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)–University Hospital Essen, Essen, Germany

4. IRCCS AOU di Bologna, Bologna, Italy

5. Nuclear Medicine and Diagnostic Imaging Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency (IAEA), Vienna, Austria.

Abstract

Abstract Studies with [68Ga]Ga-labeled or [18F]F-labeled fibroblast activation protein inhibitor compounds have demonstrated favorable characteristics for PET/CT imaging, making them especially interesting for digestive tumors. In this review, the recent evidence in this field and its potential clinical applications are discussed.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

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