Evaluation of the Anatomical and Radiological Morphometry of Optic Nerve and Cranium in Healthy Individuals

Abstract

This paper determined the morphometric measurements’ reference values and relationship of the optic nerve and cranium in Turkish healthy individuals according to age and sex. Five hundred fifty-nine (280 females and 279 males) patients aged from 2 to 90 years were included in this study. The measurements were taken from patients having brain magnetic resonance images in sagittal, axial, and coronal sections in the radiology department. Eyeball transverse diameter, optic nerve sheath thickness (ONST), optic chiasm length, optic chiasm width, and cranium morphometric measurements of all individuals who participated in the study were taken. Except for the width of the optic chiasm, all measurements showed significant differences between the sexes (P < 0.05). In contrast, all measurement values were higher in males than females, except for the clival angle. According to the result of Pearson correlation analysis, in which the existence of a relationship between ONST and craniometric measurements was evaluated, a low but significant correlation was found between ONST and craniometric measurements (r < 0.4; P < 0.05). In the post hoc test performed to compare the decades, it was seen that the most significant changes in our measurements were in the 2 to 10 age range and the measurement values decreased in old age. We think that revealing the age and sex-related changes in the optic nerve and cranium morphometry of our population anatomically and radiologically will be an important source in terms of creating reference values for our population.