A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT-Reference-Cited by-同舟云学术

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A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT

Published:2005-11-04 Issue:16 Volume:19 Page:1751-1760
ISSN:0269-9370
Container-title:AIDS
language:en
Short-container-title:

Author:

White Kirsten L,Margot Nicolas A,Ly John K,Chen James M,Ray Adrian S,Pavelko Martina,Wang Ruth,McDermott Martin,Swaminathan S,Miller Michael D

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference63 articles.

1. Identification of a mutation of codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2’,3’-dideoxycytidine and 2’,3’-dideoxy-3’-thiacytidine;Gu;Antimicrob Agents Chemother,1994

2. Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89;Tisdale;Antimicrob Agents Chemother,1997

3. In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA;Wainberg;Antiviral Ther,1999

4. A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation;Garcia-Lerma;J Virol,2003

5. Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy;Harrigan;J Infect Dis,2000

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1. A Combination of Amino Acid Mutations Leads to Resistance to Multiple Nucleoside Analogs in Reverse Transcriptases from HIV-1 Subtypes B and C;Antimicrobial Agents and Chemotherapy;2022-01-18

2. Elucidating molecular interactions of L-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance;Communications Biology;2019-12

3. The Impact of HIV-1 Drug Escape on the Global Treatment Landscape;Cell Host & Microbe;2019-07

4. Prevalence of K65R in patients treated with tenofovir disoproxil fumarate: recommendations based on the Frankfurt HIV Cohort Study Resistance Database (FHCS-RD);MED MICROBIOL IMMUN;2016

5. Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors;Nucleic Acids Research;2016-02-04

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