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Effect of aprepitant on kynurenine to tryptophan ratio in cART treated and cART naïve adults living with HIV

  • Published:2021-06-11 Issue:23 Volume:100 Page:e25313
  • ISSN:0025-7974
  • Container-title:Medicine
  • language:en
  • Short-container-title:

Author:

Spitsin Sergei,Pappa Vasiliki,Kinder Annemarie,Evans Dwight L.,Rappaport Jay,Douglas Steven D.

Funder

National Institute of Mental Health

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

Reference37 articles.

1. Immune suppression and immune activation in depression;Blume;Brain Behav Immun,2011

2. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease;Favre;Sci Transl Med,2010

3. Serum kynurenine-to-tryptophan ratio increases with progressive disease in HIV-infected patients;Huengsberg;Clin Chem,1998

4. Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans;Lee;AIDS,2016

5. Clinical relevance of kynurenine pathway in HIV/AIDS: an immune checkpoint at the crossroads of metabolism and inflammation;Routy;AIDS Rev,2015

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