A case report of a patient with Turner syndrome who develops catatonia secondary to psychotic symptoms

Abstract

Rationale: Turner syndrome (TS) is a genetic disorder associated with partial or complete monosomy X abnormalities; some patients may have a higher risk of psychiatric symptoms. Catatonia is associated with a wide range of life-threatening complications with complex pathogenesis; However, It very rare for patients with TS to develop psychotic symptoms and eventually progress to catatonia. This case report describes the diagnostic and therapeutic course of catatonia-associated TS. Patient concerns: In this study, we report the case of a patient with TS who initially developed sudden hallucinations, delusions, and emotional instability, followed by catatonia. Diagnoses: The patient was diagnosed with: unspecified catatonia; TS. Interventions: Treatment included administering a combination of esazolam injections and olanzapine tablets, placing a gastric tube and urinary catheter, and providing nutritional support. Outcomes: After treatment, the patient’s hallucinations, delusions, and catatonia disappeared, with no residual sequelae, and social functioning returned to normal. Lessons: For patients with TS who present with psychotic symptoms and catatonia, a comprehensive evaluation is necessary, and treatment with antipsychotics and benzodiazepines is effective.