Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection

Author:

Winer Benjamin Y.1ORCID,Shirvani-Dastgerdi Elham1ORCID,Bram Yaron2ORCID,Sellau Julie1ORCID,Low Benjamin E.3ORCID,Johnson Heath1,Huang Tiffany1,Hrebikova Gabriela1,Heller Brigitte1,Sharon Yael1,Giersch Katja4,Gerges Sherif1ORCID,Seneca Kathleen5ORCID,Pais Mihai-Alexandru1,Frankel Angela S.2,Chiriboga Luis6ORCID,Cullen John7ORCID,Nahass Ronald G.5ORCID,Lutgehetmann Marc8ORCID,Toettcher Jared E.1ORCID,Wiles Michael V.3,Schwartz Robert E.2,Ploss Alexander1ORCID

Affiliation:

1. Department of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Washington Road, Princeton, NJ 08544, USA.

2. Division of Gastroenterology and Hepatology, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA.

3. Department of Technology Evaluation and Development, The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609–1500 USA.

4. Department of Internal Medicine, Center for Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

5. Infectious Disease Care, 105 Raider Boulevard, Hillsborough, NJ 08844, USA.

6. Department of Pathology, New York University Medical Center, New York, NY 10016, USA.

7. Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, Raleigh, NC 27607, USA.

8. Institute of Microbiology, Virology and Hygiene, University Medical Hospital, Hamburg-Eppendorf, Hamburg, Germany.

Abstract

An inbred mouse model for HDV infection can be used to study virally induced immune responses and for testing antiviral therapeutics.

Funder

National Institutes of Health

American Cancer Society

National Cancer Institute

National Institute of Allergy and Infectious Diseases

Burroughs Wellcome Fund

Deutsche Forschungsgemeinschaft

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Cited by 35 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3