Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody-Reference-Cited by-同舟云学术

Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody

Published:2017-04-05 Issue:384 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Mire Chad E.¹²^ORCID,Geisbert Joan B.¹²^ORCID,Borisevich Viktoriya¹²,Fenton Karla A.¹²,Agans Krystle N.¹²,Flyak Andrew I.³^ORCID,Deer Daniel J.¹²,Steinkellner Herta⁴^ORCID,Bohorov Ognian⁵,Bohorova Natasha⁵,Goodman Charles⁵,Hiatt Andrew⁵,Kim Do H.⁵^ORCID,Pauly Michael H.⁵,Velasco Jesus⁵,Whaley Kevin J.⁴,Crowe James E.³⁶⁷^ORCID,Zeitlin Larry⁵^ORCID,Geisbert Thomas W.¹²^ORCID

Affiliation:

1. Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA.

2. Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.

3. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

4. Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, 1190 Vienna, Austria.

5. Mapp Biopharmaceutical Inc., San Diego, CA 92121, USA.

6. Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

7. Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Abstract

A single mAb is an effective therapy in nonhuman primates infected with Marburg or Ravn virus.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference36 articles.

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2. M. Leitenberg R. A. Zilinskas The Soviet Biological Weapons Program: A History (Harvard Univ. Press 2012).

3. The therapeutic monoclonal antibody market

4. Return to the Past: The Case for Antibody-Based Therapies in Infectious Diseases

5. Preventing infectious disease with passive immunization

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