Inhibition of hyperglycolysis in mesothelial cells prevents peritoneal fibrosis

Author:

Si Meijun12ORCID,Wang Qianqian13ORCID,Li Yin1,Lin Hongchun1,Luo Dan1ORCID,Zhao Wenbo1ORCID,Dou Xianrui4,Liu Jun5,Zhang Hui5,Huang Yong6,Lou Tanqi1,Hu Zhaoyong2ORCID,Peng Hui1ORCID

Affiliation:

1. Nephrology Division, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.

2. Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

3. Nephrology Division, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China.

4. Nephrology Division, Shunde Hospital of Southern Medical University, Foshan 528300, China.

5. Institute of Human Virology and Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.

6. Division of Gastrointestinal Surgery, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.

Abstract

Peritoneal fibrosis due to hyperglycolysis in mesothelial cells can be prevented by a triad of microRNAs.

Funder

National Institutes of Health

National Natural Science Foundation of China

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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