Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection-Reference-Cited by-同舟云学术

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection

Published:2015-04-08 Issue:282 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

He Shanshan¹,Lin Billy¹,Chu Virginia¹,Hu Zongyi¹,Hu Xin²,Xiao Jingbo²,Wang Amy Q.²,Schweitzer Cameron J.¹,Li Qisheng¹,Imamura Michio³,Hiraga Nobuhiko³,Southall Noel²,Ferrer Marc²,Zheng Wei²,Chayama Kazuaki³,Marugan Juan J.²,Liang T. Jake¹

Affiliation:

1. Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

2. National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.

3. Department of Medicine and Molecular Sciences, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 730-0053, Japan.

Abstract

Over-the-counter allergy drug chlorcyclizine was identified and characterized as an anti-HCV drug in vitro and in vivo.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference49 articles.

1. Current and Future Therapies for Hepatitis C Virus Infection

2. Global control of hepatitis C: where challenge meets opportunity

3. Pathogenesis, Natural History, Treatment, and Prevention of Hepatitis C

4. Hepatitis C Virus Testing of Persons Born During 1945–1965: Recommendations From the Centers for Disease Control and Prevention

5. Current progress in development of hepatitis C virus vaccines

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