IL-25: The Missing Link Between Allergy, Viral Infection, and Asthma?

Author:

Andreakos Evangelos1,Papadopoulos Nikolaos G.23

Affiliation:

1. Department of Immunology, Center for Clinical and Translational Research, Biomedical Research Foundation, Academy of Athens, Athens 11527, Greece.

2. Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children’s Hospital, University of Manchester, Manchester M13 9WL, UK.

3. Allergy Department, 2nd Pediatric Clinic, Athens General Children’s Hospital “P&A Kyriakou,” University of Athens, Athens 11527, Greece.

Abstract

Interleukin 25 boosts proinflammatory and proasthmatic responses in the allergic lung and emerges as a key determinant of virally induced asthma exacerbations and as a therapeutic target for asthma (Beale et al ., this issue).

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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1. Type 2 cytokine genes as allergic asthma risk factors after viral bronchiolitis in early childhood;Frontiers in Immunology;2023-01-06

2. Thymic stromal lymphopoietin and alarmins as possible therapeutical targets for asthma;Current Opinion in Allergy & Clinical Immunology;2021-10-01

3. IL-25 (IL-17E) in epithelial immunology and pathophysiology;Journal of Allergy and Clinical Immunology;2021-07

4. Initiation and Pathogenesis of Severe Asthma with Fungal Sensitization;Cells;2021-04-15

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