The long-acting integrase inhibitor GSK744 protects macaques from repeated intravaginal SHIV challenge

Author:

Radzio Jessica1,Spreen William2,Yueh Yun Lan2,Mitchell James1,Jenkins Leecresia1,García-Lerma J. Gerardo1,Heneine Walid1

Affiliation:

1. Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.

2. GlaxoSmithKline, Research Triangle Park, NC 27709, USA.

Abstract

The long-acting GSK744 HIV integrase inhibitor prevents vaginal SHIV infection in pigtail macaques.

Funder

CDC

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference24 articles.

1. UNAIDS report on the global AIDS epidemic 2013 http://www.unaids.org/sites/default/files/en/media/unaids/contentassets/documents/epidemiology/2013/gr2013/UNAIDS_Global_Report_2013_en.pdf.

2. Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women

3. Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

4. Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana

5. Preexposure Prophylaxis for HIV Infection among African Women

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