An injectable shear-thinning biomaterial for endovascular embolization

Author:

Avery Reginald K.123,Albadawi Hassan4,Akbari Mohsen135,Zhang Yu Shrike135,Duggan Michael J.6,Sahani Dushyant V.7,Olsen Bradley D.8,Khademhosseini Ali1359,Oklu Rahmi110

Affiliation:

1. Biomaterials Innovation Research Center, Department of Medicine, Division of Engineering in Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02139, USA.

2. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

3. Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.

4. Department of Surgery, Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

5. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

6. Department of Surgery, Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02144, USA.

7. Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

8. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

9. Department of Physics, King Abdulaziz University, Jeddah, Saudi Arabia.

10. Division of Vascular and Interventional Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Abstract

An engineered shear-thinning biomaterial is used as an embolic agent for vascular occlusion as treatment for bleeding.

Funder

NIH Interdepartmental Biotechnology Training Program

U.S. Army Research Office

National Cancer Institute

NSF

IMMODGEL

NIH

Mayo Clinic

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference60 articles.

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4. Mesenteric Embolization for Lower Gastrointestinal Bleeding

5. Mesenteric angiography for the localization and treatment of acute lower gastrointestinal bleeding;Karanicolas P. J.;Can. J. Surg.,2008

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