Serum microRNAs are early indicators of survival after radiation-induced hematopoietic injury

Author:

Acharya Sanket S.1,Fendler Wojciech2,Watson Jacqueline1,Hamilton Abigail1,Pan Yunfeng1,Gaudiano Emily1,Moskwa Patryk3,Bhanja Payel4,Saha Subhrajit4,Guha Chandan45,Parmar Kalindi1,Chowdhury Dipanjan1

Affiliation:

1. Department of Radiation Oncology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

2. Department of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Lodz 91-738, Poland.

3. Department of Internal Medicine A, Medical University of Greifswald, Ferdinand-Sauerbruchstrasse, Greifswald 17475, Germany.

4. Department of Radiation Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA.

5. Department of Pathology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA.

Abstract

Serum miRNAs can predict long-term radiation-induced hematopoietic injury immediately after radiation and thereby facilitate timely medical intervention and improve overall survival of exposed individuals.

Funder

American Cancer Society

National Institute of Allergy and Infectious Diseases

Mary Kay Foundation

Leukemia & Lymphoma Society Scholar Grant

Foundation for Polish Science

Ann-Fuller Foundation

National Science Center of Poland

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference38 articles.

1. Scenario of a dirty bomb in an urban environment and acute management of radiation poisoning and injuries;Chin F. K.C.;Singapore Med. J.,2007

2. Medical Management of the Acute Radiation Syndrome: Recommendations of the Strategic National Stockpile Radiation Working Group

3. Modulation of Radiation Injury

4. Management of ionizing radiation injuries and illnesses, part 4: Acute radiation syndrome;Christensen D. M.;J. Am. Osteopath. Assoc.,2014

5. Hematopoietic stem cell compartment: Acute and late effects of radiation therapy and chemotherapy

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