Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

Author:

Benham Helen12,Nel Hendrik J.1,Law Soi Cheng1,Mehdi Ahmed M.1,Street Shayna1,Ramnoruth Nishta1,Pahau Helen1,Lee Bernett T.3,Ng Jennifer1,G. Brunck Marion E.1,Hyde Claire1,Trouw Leendert A.4,Dudek Nadine L.5,Purcell Anthony W.5,O’Sullivan Brendan J.1,Connolly John E.3,Paul Sanjoy K.6,Lê Cao Kim-Anh1,Thomas Ranjeny1

Affiliation:

1. University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia.

2. University of Queensland School of Medicine, Brisbane, Queensland 4102, Australia.

3. Singapore Immunology Network, Agency for Science, Technology and Research, 8A Biomedical Grove, Immunos Building, Level 3, Biopolis, 138673 Singapore, Singapore.

4. Department of Rheumatology, Leiden University Medical Center, Leiden 2333, Netherlands.

5. Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

6. Queensland Clinical Trials & Biostatistics Centre, School of Population Health, The University of Queensland, Brisbane, Queensland 4006, Australia.

Abstract

Citrullinated peptide-exposed DCs induced immune regulatory effects in HLA risk genotype–positive RA patients.

Funder

Princess Alexandra Hospital Foundation

Australian Research Council

National Health and Medical Research Council

NHMRC Peter Doherty Fellowship

NHMRC Senior Research Fellow

Australian Cancer Research Foundation

De Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) ZonMw Vidi

Queensland Government Innovation Start-Up Scheme

AusIndustry Biotechnology Innovation Fund

Arthritis Queensland

Queensland Government Smart State Fellowship and Arthritis Queensland

Therapeutic Innovation Australia

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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