Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates-Reference-Cited by-同舟云学术

Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates

Published:2021-03-03 Issue:583 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Darricarrère Nicole¹^ORCID,Qiu Yu¹,Kanekiyo Masaru²^ORCID,Creanga Adrian²^ORCID,Gillespie Rebecca A.²^ORCID,Moin Syed M.²,Saleh Jacqueline¹^ORCID,Sancho Jose¹,Chou Te-Hui¹^ORCID,Zhou Yanfeng¹^ORCID,Zhang Ruijun¹^ORCID,Dai Shujia¹^ORCID,Moody Anthony³^ORCID,Saunders Kevin O.³^ORCID,Crank Michelle C.²^ORCID,Mascola John R.²^ORCID,Graham Barney S.²^ORCID,Wei Chih-Jen¹^ORCID,Nabel Gary J.¹^ORCID

Affiliation:

1. Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.

2. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

3. Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.

Abstract

Nonhuman primates immunized with adjuvanted stabilized headless HA stem nanoparticles generated influenza-specific broadly neutralizing antibodies.

Funder

National Institute of Allergy and Infectious Diseases

Sanofi

Publisher

American Association for the Advancement of Science (AAAS)

Subject