Notch4 Normalization Reduces Blood Vessel Size in Arteriovenous Malformations-Reference-Cited by-同舟云学术

Notch4 Normalization Reduces Blood Vessel Size in Arteriovenous Malformations

Published:2012-01-18 Issue:117 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Murphy Patrick A.¹,Kim Tyson N.¹,Lu Gloria¹,Bollen Andrew W.²,Schaffer Chris B.³,Wang Rong A.¹

Affiliation:

1. Laboratory for Accelerated Vascular Research, Division of Vascular Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA .

2. Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.

3. Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.

Abstract

Normalization of Notch expression restores enlarged blood vessels to microvessels through EphB4-mediated reprogramming of arterial endothelial cells.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference35 articles.

1. Vascular malformations

2. Arteriovenous Malformations of the Brain

3. Regulation of vascular morphogenesis by Notch signaling

4. Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

5. Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity

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