Epstein-Barr Virus: An Important Vaccine Target for Cancer Prevention

Author:

Cohen Jeffrey I.1,Fauci Anthony S.1,Varmus Harold2,Nabel Gary J.13

Affiliation:

1. National Institute of Allergy and Infectious Diseases (NIAID), U.S. National Institutes of Health (NIH), Bethesda, MD 20892, USA.

2. National Cancer Institute, NIH, Bethesda, MD 20892, USA.

3. Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA.

Abstract

Clinical studies should focus on prevention of Epstein-Barr virus–associated cancers and infectious mononucleosis, facilitated by identification of disease-predictive surrogate markers.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference10 articles.

1. Participants at the meeting were Richard Ambinder Johns Hopkins University; Hugh Auchincloss NIH; Henry Balfour University of Minnesota; Alan Bernstein HIV Vaccine Enterprise; Wei Bu NIH; Corey Casper Fred Hutchinson Cancer Research Center; Jeffrey Cohen NIH; Lawrence Corey Fred Hutchinson Cancer Research Center; Martine Denise Sanofi Pasteur; Geraldina Dominguez NIH; Anthony Fauci NIH; Gregory Hayes Medimmune; Carole Heilman NIH; Bahija Jallal Medimmune; George Kemble Medimmune; Rajiv Khanna Queensland Institute of Medical Research; Elliott Kieff Harvard Medical School; Philip Krause Food and Drug Administration; Catherine Laughlin NIH; Douglas Lowy NIH; Edward Mocarski Emory Vaccine Center; Gary Nabel NIH; Nancy Raab-Traub University of North Carolina; Betsy Read-Connole NIH; Steven Reed Infectious Disease Research Institute; Alan Rickinson University of Birmingham UK; Cliona Rooney Baylor College of Medicine; Dinah Singer NIH; Joseph Sliman Medimmune; Harold Varmus NIH; Fred Wang Harvard Medical School; Amy Weiner Gates Foundation; Jennifer Woo Medimmune; Robert Yarchoan NIH; and Kathryn Zoon NIH.

2. Epstein–Barr Virus Infection

3. Recombinant gp350 Vaccine for Infectious Mononucleosis: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial to Evaluate the Safety, Immunogenicity, and Efficacy of an Epstein‐Barr Virus Vaccine in Healthy Young Adults

4. A Phase I Trial of Epstein-Barr Virus Gp350 Vaccine for Children With Chronic Kidney Disease Awaiting Transplantation

5. Phase I Trial of a CD8 + T-Cell Peptide Epitope-Based Vaccine for Infectious Mononucleosis

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