A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis

Published:2010-10-13 Issue:53 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Bertholet Sylvie¹,Ireton Gregory C.¹,Ordway Diane J.²,Windish Hillarie Plessner¹,Pine Samuel O.¹,Kahn Maria¹,Phan Tony¹,Orme Ian M.²,Vedvick Thomas S.¹,Baldwin Susan L.¹,Coler Rhea N.¹,Reed Steven G.¹

Affiliation:

1. Infectious Disease Research Institute, 1124 Columbia Street, Suite 400, Seattle, WA 98104, USA.

2. Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80253, USA.

Abstract

A vaccine with a four-protein fusion peptide from Mycobacterium tuberculosis effectively boosts the current childhood TB vaccine and protects against drug-resistant TB.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference27 articles.

1. World Health Organization Anti-Tuberculosis Drug Resistance in the World: Fourth Global Report (World Health Organization Geneva Switzerland 2008). http://www.who.int/tb/publications/2008/drs_report4_26feb08.pdf

2. The success and failure of BCG — implications for a novel tuberculosis vaccine

3. Immunology of Tuberculosis

4. Identification of Human T Cell Antigens for the Development of Vaccines againstMycobacterium tuberculosis

5. Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations

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