Recurrent epimutation of SDHC in gastrointestinal stromal tumors-Reference-Cited by-同舟云学术

Recurrent epimutation of SDHC in gastrointestinal stromal tumors

Published:2014-12-24 Issue:268 Volume:6 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Killian J. Keith¹,Miettinen Markku²,Walker Robert L.¹,Wang Yonghong¹,Zhu Yuelin Jack¹,Waterfall Joshua J.¹,Noyes Natalia¹,Retnakumar Parvathy¹,Yang Zhiming²,Smith William I.³,Killian M. Scott⁴,Lau C. Christopher¹,Pineda Marbin¹,Walling Jennifer¹,Stevenson Holly¹,Smith Carly⁵,Wang Zengfeng²,Lasota Jerzy²,Kim Su Young⁶,Boikos Sosipatros A.⁶,Helman Lee J.⁶,Meltzer Paul S.¹

Affiliation:

1. Genetics Branch, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD 20892, USA.

2. Laboratory of Pathology, Center for Cancer Research, NIH, Bethesda, MD 20892, USA.

3. Department of Pathology, Suburban Hospital, Bethesda, MD 20814, USA.

4. University of South Dakota, Vermillion, SD 57069, USA.

5. National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892, USA.

6. Pediatric Oncology Branch, Center for Cancer Research, NIH, Bethesda, MD 20892, USA.

Abstract

Methylation of the SDH gene explains the loss of SDH gene expression in SDH wild-type gastrointestinal stromal tumors.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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