1. Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA.
2. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
3. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02115, USA.
4. Genentech Inc., South San Francisco, CA 94080, USA.
5. Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02115, USA.
6. Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.