Escaping ALK Inhibition: Mechanisms of and Strategies to Overcome Resistance-Reference-Cited by-同舟云学术

Escaping ALK Inhibition: Mechanisms of and Strategies to Overcome Resistance

Published:2012-02-08 Issue:120 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Lovly Christine M.¹,Pao William¹²

Affiliation:

1. Department of Medicine, Division of Hematology and Oncology, Vanderbilt University, Nashville, TN 37232, USA.

2. Vanderbilt-Ingram Cancer Center, Nashville, TN 37232–6307, USA.

Abstract

Two recent studies offer insights on how cancer cells develop resistance to targeted therapies and possible ways to battle this therapeutic bottleneck.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference31 articles.

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4. Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

5. Fusion of a Kinase Gene, ALK , to a Nucleolar Protein Gene, NPM , in Non-Hodgkin's Lymphoma

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