PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis

Author:

Chen Ray Y.1,Dodd Lori E.2,Lee Myungsun3,Paripati Praveen4,Hammoud Dima A.5,Mountz James M.6,Jeon Doosoo7,Zia Nadeem6,Zahiri Homeira5,Coleman M. Teresa6,Carroll Matthew W.1,Lee Jong Doo8,Jeong Yeon Joo9,Herscovitch Peter10,Lahouar Saher4,Tartakovsky Michael11,Rosenthal Alexander11,Somaiyya Sandeep4,Lee Soyoung3,Goldfeder Lisa C.1,Cai Ying1,Via Laura E.1,Park Seung-Kyu7,Cho Sang-Nae312,Barry Clifton E.113

Affiliation:

1. Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

2. Biostatistics Research Branch, NIAID, NIH, Bethesda, MD 20892, USA.

3. International Tuberculosis Research Center, Changwon 631-710, South Korea.

4. NET Esolutions Corporation (NETE), NETE-FGI Imaging Team, McLean, VA 22102, USA.

5. Division of Diagnostic Radiology, Clinical Center, NIH, Bethesda, MD 20892, USA.

6. Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15260, USA.

7. National Masan Hospital, Changwon 631-710, South Korea.

8. Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.

9. Department of Diagnostic Radiology, Pusan National University School of Medicine, Busan 609-735, South Korea.

10. PET Department, Clinical Center, NIH, Bethesda, MD 20892, USA.

11. Office of Cyber Infrastructure and Computational Biology, NIAID, NIH, Bethesda, MD 20892, USA.

12. Department of Microbiology and Institute of Immunology and Immunological Disease, Yonsei University College of Medicine, Seoul 120-752, South Korea.

13. Institute of Infectious Disease and Molecular Medicine, and the Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Rondebosch 7701, South Africa.

Abstract

PET/CT imaging in humans with TB correlates with drug response and final treatment outcomes.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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