Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans-Reference-Cited by-同舟云学术

Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans

Published:2013-02-13 Issue:172 Volume:5 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Titus Shiny¹²,Li Fang¹²,Stobezki Robert¹²,Akula Komala¹²,Unsal Evrim¹²³,Jeong Kyungah¹²,Dickler Maura⁴,Robson Mark⁴,Moy Fred¹²⁵,Goswami Sumanta¹²⁶,Oktay Kutluk¹²

Affiliation:

1. Institute for Reproductive Medicine and Fertility Preservation, and Laboratory of Molecular Reproduction, Department of Obstetrics and Gynecology, New York Medical College, Rye, NY 10580, USA.

2. Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY 10595, USA.

3. Department of Medical Biology and Genetics, Istanbul Bilim University School of Medicine, Ankara 34349, Turkey.

4. Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill Medical College of Cornell University, New York, NY 10021, USA.

5. Biometrics, Data Management and PK/PD Unit, Department of Pathology, New York Medical College, Valhalla, NY 10595, USA.

6. Department of Biology, Yeshiva University, New York, NY 10033, USA.

Abstract

DNA double-strand break repair has a central role in oocyte aging.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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