Metformin as adjunct antituberculosis therapy

Author:

Singhal Amit1,Jie Liu1,Kumar Pavanish1,Hong Gan Suay2,Leow Melvin Khee-Shing34,Paleja Bhairav1,Tsenova Liana56,Kurepina Natalia5,Chen Jinmiao1,Zolezzi Francesca1,Kreiswirth Barry5,Poidinger Michael17,Chee Cynthia2,Kaplan Gilla58,Wang Yee Tang2,De Libero Gennaro19

Affiliation:

1. Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.

2. Tuberculosis Control Unit, Tan Tock Seng Hospital, Singapore 308089, Singapore.

3. Department of Endocrinology, Tan Tock Seng Hospital, Singapore 308433, Singapore.

4. Singapore Institute for Clinical Sciences, A*STAR, Singapore 117609, Singapore.

5. Public Health Research Institute at New Jersey Medical School, Rutgers University, Newark, NJ 07103, USA.

6. New York City College of Technology, Brooklyn, NY 11201, USA.

7. Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore.

8. Bill & Melinda Gates Foundation, Seattle, WA 98109, USA.

9. University Hospital Basel, University of Basel, Basel 4031, Switzerland.

Abstract

Metformin can be repurposed as host-directed therapy for tuberculosis.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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