A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples-Reference-Cited by-同舟云学术

A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples

Published:2020-08-12 Issue:556 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Dao Thi Viet Loan¹²^ORCID,Herbst Konrad³^ORCID,Boerner Kathleen²⁴,Meurer Matthias³^ORCID,Kremer Lukas PM³⁵⁶^ORCID,Kirrmaier Daniel³⁵,Freistaedter Andrew¹²^ORCID,Papagiannidis Dimitrios³^ORCID,Galmozzi Carla³⁶^ORCID,Stanifer Megan L.²^ORCID,Boulant Steeve²⁵^ORCID,Klein Steffen¹²^ORCID,Chlanda Petr¹²^ORCID,Khalid Dina²^ORCID,Barreto Miranda Isabel²,Schnitzler Paul²,Kräusslich Hans-Georg²⁴^ORCID,Knop Michael³⁵⁶^ORCID,Anders Simon³^ORCID

Affiliation:

1. Schaller Research Groups, Department of Infectious Diseases, Virology, Heidelberg University, Heidelberg, Germany.

2. Department of Infectious Diseases, Virology, Heidelberg University, Heidelberg, Germany.

3. Center for Molecular Biology of Heidelberg University (ZMBH), Heidelberg, Germany.

4. German Center for Infection Research (DZIF), Heidelberg, Germany.

5. German Cancer Research Center (DKFZ), Heidelberg, Germany.

6. DKFZ-ZMBH Alliance, Heidelberg, Germany.

Abstract

A colorimetric isothermal RNA amplification method was shown to detect SARS-CoV-2 RNA in clinical samples with excellent sensitivity and specificity.

Funder

Deutsches Krebsforschungszentrum

Chica and Heinz Schaller-Stiftung

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference49 articles.

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4. Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility

5. Loop-mediated isothermal amplification of DNA

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