Vaccines inducing immunity to Lassa virus glycoprotein and nucleoprotein protect macaques after a single shot-Reference-Cited by-同舟云学术

Vaccines inducing immunity to Lassa virus glycoprotein and nucleoprotein protect macaques after a single shot

Published:2019-10-02 Issue:512 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Mateo Mathieu¹²^ORCID,Reynard Stéphanie¹²^ORCID,Carnec Xavier¹²,Journeaux Alexandra¹²,Baillet Nicolas¹²,Schaeffer Justine¹²,Picard Caroline¹²,Legras-Lachuer Catherine³^ORCID,Allan Richard³,Perthame Emeline⁴^ORCID,Hillion Kenzo-Hugo⁴^ORCID,Pietrosemoli Natalia⁴,Dillies Marie-Agnès⁴,Barrot Laura⁵,Vallve Audrey⁵,Barron Stéphane⁵,Fellmann Lyne⁶,Gaillard Jean-Charles⁷,Armengaud Jean⁷^ORCID,Carbonnelle Caroline⁵^ORCID,Raoul Hervé⁵,Tangy Frédéric⁸^ORCID,Baize Sylvain¹²^ORCID

Affiliation:

1. Unité de Biologie des Infections Virales Emergentes, Institut Pasteur, Lyon, France.

2. Centre International de Recherche en Infectiologie (CIRI), Université de Lyon, INSERM U1111, Ecole Normale Supérieure de Lyon, Université Lyon 1, CNRS UMR5308, Lyon, France.

3. ViroScan3D SAS, Trévoux, France.

4. Bioinformatics and Biostatistics Hub–Department of Computational Biology, USR 3756 CNRS, Institut Pasteur, Paris, France.

5. Laboratoire P4 INSERM–Jean Mérieux, INSERM US003, Lyon, France.

6. SILABE, Université de Strasbourg, Fort Foch, Niederhausbergen, France.

7. Laboratoire Innovations Technologiques pour la Détection et le Diagnostic (LI2D), Service de Pharmacologie et Immunoanalyse (SPI), Commissariat à l’Energie Atomique, Bagnols-sur-Cèze, France.

8. Viral Genomics and Vaccination, Institut Pasteur, CNRS UMR-3569, Paris, France.

Abstract

A single dose of vaccines eliciting cellular and humoral immunity to Lassa virus glycoprotein and nucleoprotein protects cynomolgus monkeys.

Funder

Institut Pasteur

Fondation pour l’Innovation en Infectiologie

Labex ECOFECT

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference51 articles.