Force-induced gene up-regulation does not follow the weak power law but depends on H3K9 demethylation-Reference-Cited by-同舟云学术

Force-induced gene up-regulation does not follow the weak power law but depends on H3K9 demethylation

Published:2020-04-03 Issue:14 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Sun Jian¹^ORCID,Chen Junwei¹²^ORCID,Mohagheghian Erfan¹,Wang Ning¹^ORCID

Affiliation:

1. Department of Mechanical Science and Engineering, The Grainger College of Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

2. Laboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.

Abstract

Rapid up-regulation of endogenous mechanoresponsive genes by force depends on demethylation of histone H3 lysine-9 trimethylation.

Funder

National Institute of General Medical Sciences

National Natural Science Foundation of China

Huazhong University of Science and Technology

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference41 articles.

1. Growth Factors, Matrices, and Forces Combine and Control Stem Cells