Prevention and treatment of autoimmune diseases with plant virus nanoparticles

Author:

Zampieri Roberta12ORCID,Brozzetti Annalisa3ORCID,Pericolini Eva4ORCID,Bartoloni Elena3,Gabrielli Elena3,Roselletti Elena3,Lomonosoff George5ORCID,Meshcheriakova Yulia5,Santi Luca6ORCID,Imperatori Francesca6,Merlin Matilde1,Tinazzi Elisa7,Dotta Francesco8,Nigi Laura89ORCID,Sebastiani Guido89ORCID,Pezzotti Mario1ORCID,Falorni Alberto3ORCID,Avesani Linda1ORCID

Affiliation:

1. Department of Biotechnology, University of Verona, Verona, Italy.

2. Diamante srl, Strada Le Grazie, 15, 37134 Verona, Italy.

3. Department of Medicine, University of Perugia, Perugia, Italy.

4. Department of Surgical, Medical, Dental and Morphological Sciences with interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.

5. Department of Biological Chemistry, John Innes Centre, Norwich, UK.

6. Department of Agriculture and Forest Sciences, University of La Tuscia, Viterbo, Italy.

7. Department of Medicine, University of Verona, Verona, Italy.

8. Diabetes Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.

9. Umberto Di Mario Foundation ONLUS, Toscana Life Sciences, Siena, Italy.

Abstract

We describe the design and testing of candidates for therapeutic autoimmune disease biopharmaceuticals built from plant viruses.

Funder

Biotechnology and Biological Sciences Research Council

MIUR

BBSRC Institute Strategic Programme Grants

BBRC Institute Strategic Programme Grants

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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