Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO 3 nanoformulation triggers ferroptosis in target tumor cells-Reference-Cited by-同舟云学术

Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO 3 nanoformulation triggers ferroptosis in target tumor cells

Published:2020-05 Issue:18 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Xue Chen-Cheng¹^ORCID,Li Meng-Huan¹^ORCID,Zhao Yang²,Zhou Jun¹,Hu Yan³,Cai Kai-Yong³,Zhao Yanli⁴^ORCID,Yu Shu-Hong²^ORCID,Luo Zhong¹^ORCID

Affiliation:

1. School of Life Science, Chongqing University, Chongqing 400044, P. R. China.

2. Division of Nanomaterials and Chemistry, Hefei National Laboratory for Physical Sciences at the Microscale, CAS Center for Excellence in Nanoscience, Collaborative Innovation Center of Suzhou Nano Science and Technology, Department of Chemistry, Hefei Science Center of CAS, University of Science and Technology of China, Hefei, 230026 China.

3. Key Laboratory of Biorheological Science and Technology, Ministry of Education, Chongqing University, Chongqing 400044, P. R. China.

4. Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371 Singapore.

Abstract

This study describes a ferroptosis/apoptosis-based treatment strategy via the cooperation between Fe 2+ and doxorubicin.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

National key R&D program of China

People’s Livelihood Special Innovation Projects of Chongqing CSTC

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference54 articles.