ACSL3–PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression-Reference-Cited by-同舟云学术

ACSL3–PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression

Published:2020-10-30 Issue:44 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Rossi Sebastiano Matteo¹^ORCID,Pozzato Chiara¹,Saliakoura Maria¹,Yang Zhang²,Peng Ren-Wang²^ORCID,Galiè Mirco³^ORCID,Oberson Kevin¹,Simon Hans-Uwe¹⁴^ORCID,Karamitopoulou Evanthia⁵,Konstantinidou Georgia¹^ORCID

Affiliation:

1. Institute of Pharmacology, University of Bern, 3010 Bern, Switzerland.

2. Division of General Thoracic Surgery, Inselspital, Bern University Hospital, 3008 Bern, Switzerland.

3. Department of Neuroscience, Biomedicine and Movement, University of Verona, 37134 Verona, Italy.

4. Department of Clinical Immunology and Allergology, Sechenov University, Moscow, Russia.

5. Institute of Pathology, University of Bern, 3008 Bern, Switzerland.

Abstract

Pharmacological inhibition of PAI-1 strongly enhances chemo- and immunotherapeutic response against PDAC.

Funder

Swiss National Science Foundation

Helmut-Horten Stiftung

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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