Mechanistic reconstruction of glycoprotein secretion through monitoring of intracellular N-glycan processing-Reference-Cited by-同舟云学术

Mechanistic reconstruction of glycoprotein secretion through monitoring of intracellular N-glycan processing

Published:2019-11 Issue:11 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Arigoni-Affolter Ilaria¹^ORCID,Scibona Ernesto²^ORCID,Lin Chia-Wei¹^ORCID,Brühlmann David³,Souquet Jonathan³,Broly Hervé³,Aebi Markus¹^ORCID

Affiliation:

1. Institute of Microbiology, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland.

2. Institute for Chemical and Bioengineering, Department of Chemistry, ETH Zürich, 8093 Zürich, Switzerland.

3. Merck Healthcare, Biotech Process Sciences, Route de Fenil 25, 1804 Corsier-sur-Vevey, Switzerland.

Abstract

Kinetic analysis of intracellular intermediates affords a mathematical model for N-glycoprotein processing and secretion.

Funder

Merck

Swiss National Science Foundation

Eidgenössische Technische Hochschule Zürich

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference56 articles.

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3. Oligosaccharyltransferase structures provide novel insight into the mechanism of asparagine-linked glycosylation in prokaryotic and eukaryotic cells

4. Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.

5. The ER-Golgi intermediate compartment (ERGIC): in search of its identity and function

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