PES1 is a critical component of telomerase assembly and regulates cellular senescence-Reference-Cited by-同舟云学术

PES1 is a critical component of telomerase assembly and regulates cellular senescence

Published:2019-05-03 Issue:5 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Cheng Long¹^ORCID,Yuan Bin¹²^ORCID,Ying Sunyang¹^ORCID,Niu Chang¹³^ORCID,Mai Hongxu¹,Guan Xin¹,Yang Xiaohui⁴^ORCID,Teng Yan⁵,Lin Jing⁶^ORCID,Huang Junjian¹,Jin Rui¹,Wu Jun⁷,Liu Bo⁷^ORCID,Chang Shaohong⁷,Wang Enqun⁸,Zhang Chunxia⁸,Hou Ning⁵,Cheng Xuan⁵,Xu Danyang¹³,Yang Xiao⁵^ORCID,Gao Shan¹⁴^ORCID,Ye Qinong¹^ORCID

Affiliation:

1. Department of Medical Molecular Biology, Beijing Institute of Biotechnology, Collaborative Innovation Center for Cancer Medicine, Beijing 100850, China.

2. Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.

3. Department of Biochemistry, College of Life Sciences, Capital Normal University, Beijing 100048, China.

4. CAS Key Laboratory of Biomedical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.

5. State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.

6. First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, China.

7. Department of Microorganism Engineering, Beijing Institute of Biotechnology, Beijing 100071, China.

8. Department of Stomatology, Anqing Municipal Hospital of Anhui Medical University, Anqing, Anhui 246003, China.

Abstract

PES1 is a new component of telomerase assembly that regulates telomerase activity, telomere length, and cellular senescence.

Funder

National Natural Science Foundation of China

Beijing Municipal Natural Science Foundation

National Key Research and Development Program of China

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference50 articles.

1. Telomere length maintenance in cancer:At the crossroad between telomerase and alternative lengthening of telomeres (ALT);De Vitis M.;Int. J. Mol. Sci.,2018

2. Telomerase mechanism of telomere synthesis;Wu R. A.;Annu. Rev. Biochem.,2017

3. Telomere dysfunction and tumour suppression: The senescence connection;Deng Y.;Nat. Rev. Cancer,2008

4. New prospects for targeting telomerase beyond the telomere;Arndt G. M.;Nat. Rev. Cancer,2016

5. Telomerase inhibitors from natural products and their anticancer potential;Ganesan K.;Int. J. Mol. Sci.,2017

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