Endosomal sorting drives the formation of axonal prion protein endoggresomes-Reference-Cited by-同舟云学术

Endosomal sorting drives the formation of axonal prion protein endoggresomes

Published:2021-12-24 Issue:52 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Chassefeyre Romain¹²³^ORCID,Chaiamarit Tai¹²³^ORCID,Verhelle Adriaan¹²³^ORCID,Novak Sammy Weiser⁴,Andrade Leonardo R.⁴^ORCID,Leitão André D. G.¹²³^ORCID,Manor Uri⁴^ORCID,Encalada Sandra E.¹²³^ORCID

Affiliation:

1. Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.

2. Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA 92037, USA.

3. Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA.

4. Waitt Advanced Biophotonics Center, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

Abstract

Mutant prion protein particles form axonal aggregates inside endolysosomes via axonal transport and endosomal fusion.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference80 articles.

1. Protein aggregate spreading in neurodegenerative diseases: Problems and perspectives

2. Propagation of Protein Aggregation in Neurodegenerative Diseases

3. Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease

4. Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

5. Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in Neurons

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Influence of metabolic stress and metformin on synaptic protein profile in SH‐SY5Y‐derived neurons;Physiological Reports;2023-11

2. Behavioral strategy shapes activation of the Vip-Sst disinhibitory circuit in visual cortex;2023-04-29

3. Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation;2023-04-01

4. Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling;2023-03-21

5. Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy;Neurobiology of Disease;2023-03