Chemical conversion of human epidermal stem cells into intestinal goblet cells for modeling mucus-microbe interaction and therapy-Reference-Cited by-同舟云学术

Chemical conversion of human epidermal stem cells into intestinal goblet cells for modeling mucus-microbe interaction and therapy

Published:2021-04-16 Issue:16 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Zhao Andong¹²^ORCID,Qin Hua¹³^ORCID,Sun Mengli¹³,Tang Mao²,Mei Jinyu²,Ma Kui¹,Fu Xiaobing¹³⁴^ORCID

Affiliation:

1. Research Center for Tissue Repair and Regeneration affiliated to the Medical Innovation Research Division and 4th Medical Center, PLA General Hospital and PLA Medical College, 28 Fu Xing Road, Haidian District, Beijing 100853, China.

2. Tianjin Medical University, Tianjin 300070, China.

3. PLA Key Laboratory of Tissue Repair and Regenerative Medicine and Beijing Key Research Laboratory of Skin Injury, Repair and Regeneration, Beijing 100048, China.

4. Research Unit of Trauma Care, Tissue Repair and Regeneration, Chinese Academy of Medical Sciences, Beijing 100048, China.

Abstract

Induced goblet cells are useful for studying the interaction of intestinal mucus layer and the gut microbiota.

Funder

National Natural Science Foundation of China

Chinese Academy of Medical Sciences

National Key Research and Development Program of China Stem Cell and Translational Research

CAMS Innovation Fund for Medical Sciences

the Military Medical Research and Development Projects

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference53 articles.

1. Intestinal Goblet Cells and Mucins in Health and Disease: Recent Insights and Progress

2. The intestinal epithelial barrier: a therapeutic target?

3. Inflammation and the Intestinal Barrier: Leukocyte–Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair

4. Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

5. Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon

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