Pathological processes in aqueous humor due to iris atrophy predispose to early corneal graft failure in humans and mice-Reference-Cited by-同舟云学术

Pathological processes in aqueous humor due to iris atrophy predispose to early corneal graft failure in humans and mice

Published:2020-05-15 Issue:20 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Yamaguchi Takefumi¹²^ORCID,Higa Kazunari¹²^ORCID,Yagi-Yaguchi Yukari¹²^ORCID,Ueda Koji³^ORCID,Noma Hisashi⁴^ORCID,Shibata Shinsuke⁵^ORCID,Nagai Toshihiro⁵,Tomida Daisuke¹,Yasu-Mimura Ririko¹²,Ibrahim Osama¹²,Matoba Ryo⁶^ORCID,Tsubota Kazuo¹²^ORCID,Hamrah Pedram⁷⁸,Yamada Jun⁹,Kanekura Kohsuke¹⁰^ORCID,Shimazaki Jun¹²^ORCID

Affiliation:

1. Department of Ophthalmology, Tokyo Dental College Ichikawa General Hospital, 5-11-13 Sugano, Ichikawa-shi, Chiba 272-8513, Japan.

2. Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

3. Project for Realization of Personalized Cancer Medicine, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-ku, Tokyo 135-8550, Japan.

4. Department of Data Science, The Institute of Statistical Mathematics, 10-3, Midori-cho, Tachikawa, Tokyo 190-0014, Japan.

5. Electron Microscope Laboratory, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.

6. DNA Chip Research Inc., Suzue Baydium 5F, 1-15-1, Kaigan, Minato-ku, Tokyo 105-0022, Japan.

7. Center for Translational Ocular Immunology, Tufts Medical Center, Tufts University School of Medicine, Tufts University, 800 Washington St., Boston, MA 02111, USA.

8. Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Tufts University, 800 Washington St., Boston, MA 02111, USA.

9. Department of Ophthalmology, Meiji University of Integrative Medicine, Hinotani 6-1, Honoda, Hiyoshi-cho, Nantan-shi, Kyoto 629-0392, Japan.

10. Department of Molecular Pathology, Tokyo Medical University, 6-1-1, Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.

Abstract

Pathological aqueous humor associated with iris atrophy leads to loss of corneal endothelial cells and corneal graft failure.

Funder

Takeda Science Foundation

Japan Research Foundation for Clinical Pharmacology

Uehara Memorial Foundation

Oyama Health Foundation

Research grant from the General Insurance Association of Japan

Rohto Research Award

Grant-in-Aid for Scientific Research of Japanese Ministry of Education, Culture, Sports, Science and Technology

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

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