Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting

Author:

Lu Xukun12ORCID,Zhang Yu12ORCID,Wang Lijuan23ORCID,Wang Leyun45ORCID,Wang Huili6ORCID,Xu Qianhua12,Xiang Yunlong12,Chen Chaolei3,Kong Feng2,Xia Weikun12ORCID,Lin Zili12,Ma Sinan47,Liu Ling2,Wang Xiangguo3ORCID,Ni Hemin3ORCID,Li Wei45ORCID,Guo Yong3ORCID,Xie Wei12ORCID

Affiliation:

1. Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.

2. Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing 100084, China.

3. College of Animal Science and Technology, Beijing University of Agriculture, Beijing 102206, China.

4. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.

5. Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.

6. Institute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.

7. College of Life Science, Northeast Agricultural University, Harbin 150030, China.

Abstract

Evolutionary analyses reveal conservation and divergence of epigenetic transition during early development across mammals.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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