A matricellular protein fibulin-4 is essential for the activation of lysyl oxidase-Reference-Cited by-同舟云学术

A matricellular protein fibulin-4 is essential for the activation of lysyl oxidase

Published:2020-11-27 Issue:48 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Noda Kazuo¹²^ORCID,Kitagawa Kaori¹^ORCID,Miki Takao¹,Horiguchi Masahito³^ORCID,Akama Tomoya O.¹,Taniguchi Takako⁴,Taniguchi Hisaaki⁴,Takahashi Kazuaki⁵^ORCID,Ogra Yasumitsu⁵^ORCID,Mecham Robert P.⁶^ORCID,Terajima Masahiko⁷^ORCID,Yamauchi Mitsuo⁷,Nakamura Tomoyuki¹^ORCID

Affiliation:

1. Department of Pharmacology, Kansai Medical University, Hirakata, Osaka 573-1010, Japan.

2. Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.

3. Department of Emergency Medicine, Japanese Red Cross Society Kyoto Daiichi Hospital, Kyoto 605-0981, Japan.

4. Division of Disease Proteomics, Institute for Enzyme Research, Tokushima University, Tokushima 770-8503, Japan.

5. Laboratory of Toxicology and Environmental Health, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.

6. Department of Cell Biology and Physiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.

7. Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA.

Abstract

A secreted protein activates a major extracellular matrix cross-linking enzyme by promoting copper ion transfer in the Golgi.

Funder

NIH Office of the Director

Takeda Science Foundation

Japan Society for the Promotion of Science

Funding Program for Next Generation World-Leading Researchers in Japan

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference42 articles.

1. Extracellular matrix 4: The elastic fiber

2. Lysine post-translational modifications of collagen

3. CROSS-LINKING IN COLLAGEN AND ELASTIN

4. Enzymatic and nonenzymatic cross‐linking of collagen and elastin

5. A Crosslinked Cofactor in Lysyl Oxidase: Redox Function for Amino Acid Side Chains

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