Dedifferentiation and neuronal repression define familial Alzheimer’s disease-Reference-Cited by-同舟云学术

Dedifferentiation and neuronal repression define familial Alzheimer’s disease

Author:

Caldwell Andrew B.¹^ORCID,Liu Qing²,Schroth Gary P.³^ORCID,Galasko Douglas R.²,Yuan Shauna H.²^ORCID,Wagner Steven L.²⁴,Subramaniam Shankar¹⁵⁶⁷^ORCID

Affiliation:

1. Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.

2. Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.

3. Illumina Inc., San Diego, CA, USA.

4. VA San Diego Healthcare System, La Jolla, CA, USA.

5. Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.

6. Department of Nanoengineering, University of California, San Diego, La Jolla, CA, USA.

7. Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA, USA.

Abstract

Neurons in familial Alzheimer’s disease undergo dedifferentiation, resulting in loss of lineage state and degeneration.

Funder

National Science Foundation

National Institutes of Health

Cure Alzheimer’s Fund

U.S. Department of Veterans Affairs

Alzheimer’s Association

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference102 articles.

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