LGP2 binds to PACT to regulate RIG-I– and MDA5-mediated antiviral responses-Reference-Cited by-同舟云学术

LGP2 binds to PACT to regulate RIG-I– and MDA5-mediated antiviral responses

Published:2019-10 Issue:601 Volume:12 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Sanchez David Raul Y.¹²^ORCID,Combredet Chantal¹^ORCID,Najburg Valérie¹,Millot Gael A.³^ORCID,Beauclair Guillaume¹^ORCID,Schwikowski Benno⁴^ORCID,Léger Thibaut⁵^ORCID,Camadro Jean-Michel⁵⁶^ORCID,Jacob Yves⁷^ORCID,Bellalou Jacques⁸^ORCID,Jouvenet Nolwenn¹^ORCID,Tangy Frédéric¹^ORCID,Komarova Anastassia V.¹^ORCID

Affiliation:

1. Unité de Génomique Virale et Vaccination, Institut Pasteur, CNRS UMR-3569, Paris, France.

2. Ecole doctorale B3MI/Paris7, Paris, France.

3. Hub de Bioinformatique et Biostatistique–C3BI, Institut Pasteur, USR 3756 CNRS, Paris, France.

4. Systems Biology Laboratory and USR 3756, Institut Pasteur and CNRS, Paris, France.

5. Mass Spectrometry Laboratory, Institut Jacques Monod, UMR 7592, Univ Paris Diderot, CNRS, Sorbonne Paris Cité, F-75205 Paris, France.

6. Mitochondria, Metals, and Oxidative Stress Group, Institut Jacques Monod, UMR 7592, Université Paris Diderot, CNRS, Sorbonne Paris Cité, F-75205 Paris, France.

7. Unité de Génétique Moléculaire des Virus à ARN, Institut Pasteur, Paris, France.

8. Platform of Recombinant Proteins in Prokaryotic Cells, Institut Pasteur, 75015, CNRS UMR 3528, Paris, France.

Abstract

The interaction between LGP2 and a component of the RNA-silencing machinery enables coordination of innate immune responses.

Funder

Fondation pour la Recherche Médicale

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference68 articles.

1. Pharmacologic Activation of the Innate Immune System to Prevent Respiratory Viral Infections